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BIOL 44209 - Exploring The Living Cell
Credit Hours: 1.00. In this five-week module, students will learn how to observe and analyze cellular structure and dynamic behavior of living cells. We will utilize live cell imaging techniques to visualize molecules, cellular structures and organelles by use of fluorescence dyes and marker proteins tagged with green fluorescent protein (GFP) and other color florescent proteins. Specimens may include whole live organisms and cultured cells, as well as live tissues and organs from animal and plant systems. Students will observe the cytoskeleton and organelles in growing cells, perform bimolecular fluorescence complementation (BiFC) analysis to see molecular interactions in the live cell and monitor protein and organelle behavior during mitosis. Live specimens will be observed under stereo-dissecting, conventional, and confocal fluorescence microscopes. Images will be acquired, digitized, and analyzed by computational programs. Typically offered Fall.
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BIOL 44210 - Introduction To DNA
Credit Hours: 1.00. In this five-week module, students will learn a survey of the major web databases for accessing DNA sequences and genomes. How to search sequences, how to make alignments, and other very basic bioinformatics. Typically offered Fall.
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BIOL 44211 - Laboratory In Anatomy And Physiology
Credit Hours: 1.00. This module will study various organs, and also discuss diseases associated with it. The heart, brain, kidney, stomach, liver etc. will be studied in detail using histology, dissection, and instrumentation. Emphasis will be placed on problem solving using various case studies. The students will be required to give presentation. Typically offered Spring.
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BIOL 44212 - Microscopy And Cell Biology
Credit Hours: 1.00. In this five-week module, students will learn how to prepare specimens for viewing by fluorescence microscopy. Specimens include mammalian tissue culture cells and zebrafish embryos. The emphasis will be on the staining of the cytoskeleton in these preparations, utilizing antibodies and fluorescence probes. The specimens will be viewed by wide-field and confocal laser scanning fluorescence microscopy. Images will be acquired, processed and analyzed by modern computational methods. Students will learn the basics of cell culture, immunocytochemistry, fluorescence microscopy, digital image processing and data analysis. At the end of the course, students prepare a PowerPoint presentation of their images and data . Typically offered Spring.
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BIOL 44214 - Microbial Pathogenesis
Credit Hours: 1.00. Successful infection by a pathogen often is mediated by the targeting of host cellular processes by virulence proteins. The identification of host pathways modulated by the pathogen is critical in the study of the pathogenic mechanisms, thus the design of any therapeutic intervention. One of the methods to identify these pathways is the use of yeast two-hybrid system. In this lab module, you will learn the principles of this powerful and widely used method. The experiments will allow you to understand the rationales of the procedures and to obtain hands-on experience in the screening process. Typically offered Spring.
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BIOL 44215 - Multidisciplinary Design Of Systems And Devices For Physiology Measurements
Credit Hours: 2.00. This physiology laboratory course will provide an opportunity for undergraduates from the College of Science (Department of Biology) to collaborate with students in other colleges (Agriculture, Education, Engineering, Health and Human Science & Technology) to experience and learn how to operate effectively as part of an interdisciplinary team to address physiological problems in the cardiovascular system, respiratory system and in biological transport. Specifically it will emphasize how these teams can use information, tools, techniques and theories from their disciplines to solve problems that are beyond the scope of any single discipline. In this process, the students will develop an appreciation of both engineering design and the classic hypothesis-driven experimental science as tools to solve complex real-world problems. This course will promote effective communication, systems thinking, laboratory skills, self-management and professional ethics. Students will learn to measure and quantify biological changes, analyze data (including statistical analysis) and interpret its meaning as it applied to the larger physiological question at hand. These skills will be necessary for teams to efficiently function in an interdisciplinary setting both in future courses and more importantly when they enter the workforce. Typically offered Fall.
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BIOL 44300 - Structure And Function In Bacteria
Credit Hours: 2.00. An examination of unique aspects of bacterial catabolism, mechanisms of pathogenesis, and the functions of cell structures and morphogenesis in survival. Emphasis is on the experimental approaches used to elucidate these processes. Typically offered Spring.
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BIOL 44400 - Human Genetics
Credit Hours: 3.00. An intermediate-level survey course of human genetics with a balanced review of both Mendelian and molecular aspects. Review of current development and application of DNA technology emphasized. Typically offered Fall.
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BIOL 44600 - Molecular Bacterial Pathogenesis
Credit Hours: 3.00. This course will focus on the interface of classical cell biology and microbiology, with emphasis on the exploitation of mammalian host cell by medically relevant pathogens, such as Yersinia, Salmonella, and Listeria. This course will cover the molecular mechanisms of infectious diseases. It will introduce modern cellular microbial strategies for studying the complex interaction between pathogens and their host cells. Topics and readings will be prepared from the most current literature. Typically offered Spring.
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BIOL 45500 - Animal Physiology
Credit Hours: 3.00. Principles of physiology illustrated by invertebrate and vertebrate systems. Respiration, ion and water balance, temperature regulation, and nervous systems. Typically offered Spring.
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BIOL 45600 - Laboratory In Animal Physiology
Credit Hours: 1.00. Laboratory experiments are designed to illustrate the principles of systems physiology. The course emphasizes the basic principles of physiology, the laboratory methods to study these principles, and the quantitative analysis of data. Permission of instructor required. Typically offered Spring.
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BIOL 46600 - Developmental Biology
Credit Hours: 3.00. The lectures and laboratories focus on what happens during the development of an organism and how we know what happens from experimental results. During the first half of the course, students spend time becoming familiar with the embryology of animals and plants by doing laboratory exercises in their lab manual. They also become adept working with chick embryos and Wisconsin Fast Plants because these are the two developing systems most students use to do their lab projects during the second half of the course. Typically offered Spring.
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BIOL 47500 - Senior Seminar In Neurobiology
Credit Hours: 1.00. Students are required to give a 30-45 minute talk based on primary journal articles chosen from a list on current developments in neuroscience or a related topic of the students choice. They are also required to read and contribute questions about each paper, and to provide anonymous feedback to each presenter. Typically offered Spring.
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BIOL 47800 - Introduction to Bioinformatics
Credit Hours: 3.00. (CS 47800 ) Bioinformatics is broadly defined as the study of molecular biological information, targeting particularly the enormous volume of DNA sequence and functional complexity embedded in entire genomes. Topics will include understanding the evolutionary organization of genes (genomics), the structure and function of gene products (proteomics), and the dynamics of gene expression in biological processes (transcriptomics). Inherently, bioinformatics is interdisciplinary, melding various applications of computational science with biology. This jointly taught course introduces analytical methods from biology, statistics and computer science that are necessary for bioinformatics investigations. The course is intended for junior and senior undergraduates from various science backgrounds. Our objective is to develop the skills of both tool users and tool designers in this important new field of research. Typically offered Fall.
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BIOL 48100 - Eukaryotic Genetics
Credit Hours: 3.00. This course presents the fundamental concepts of classical and modern molecular genetics in eukaryotic systems, using examples from the model genetic organisms, yeast, Drosophila, Caenorhabditis, Arabidopsis, maize, mice and humans. These concepts are applied to solving problems of genetic analysis. Recent advances in developmental, cancer, and behavioral genetics and genomics, and applications of genetic technology, are used to demonstrate the impact that modern genetics makes at the cutting edge of biological research. Typically offered Spring.
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BIOL 48300 - Great Issues: Environmental And Conservation Biology
Credit Hours: 3.00. Concerned with the application of ecological principles to environmental issues, the course introduces fundamental ecology, emphasizing the interplay of theoretical models, natural history, and experimentation. New research developments are stressed, with the outlook for application to environmental management and restoration. Whole-biosphere issues, such as the loss of biological diversity, frame a focus at the population level to understand local and global extinction and community stability. In-depth case studies of endangered ecosystems (both temperate and tropical), with computer modeling, field trips, and discussions of policy formulation, demonstrate the range of tools and information necessary to accomplish coexistence of humans with the rest of nature. Typically offered Fall.
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BIOL 49300 - Introduction To Ethology
Credit Hours: 3.00. (PSY 49400 ) Animal and human behavior is presented from an ethological perspective. Emphasis is on observation and description of natural behaviors, motivation, the behavioral aspects of ecology, the evolution of behavior, and the domestication of animals. Several representative groups of wild and domesticated species will be discussed and illustrated with slides and films with respect to individual and social behavior, predator-prey relationships, etc. Field trips will augment classroom work. A critical examination of popular books in ethology will be made against the background of this course. Typically offered Fall.
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BIOL 49400 - Biology Research
Credit Hours: 1.00 to 4.00. Supervised individual research performed by juniors and seniors. Project must be approved by the Honors Committee, Department of Biological Sciences. Honors Research Program students should register for BIOL 49900 . Permission of department required. Typically offered Fall Spring Summer.
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BIOL 49500 - Special Assignments
Arrange Hours and Credit. Readings, discussions, written reports, seminar presentations, and field or laboratory work provided for enrichment in special areas of the biological sciences. Permission of instructor required. Typically offered Fall Spring Summer.
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BIOL 49600 - Biology Honors Tutorial
Credit Hours: 1.00 to 4.00. Selected readings, discussions, and written reports under the guidance of a faculty tutor. Submission of honors tutorial petition and consent of faculty tutor and Honors Committee. Permission of instructor required. Typically offered Fall Spring Summer.
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BIOL 49700 - Biology Honors Seminar
Credit Hours: 1.00. Required of all students participating in honors research. Discussions and presentations of research, including seminars by those students who are completing their honors research thesis. Typically offered Spring.
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BIOL 49800 - Biology Teaching
Credit Hours: 3.00. Supervised teaching experience for juniors and seniors. Must have approval of course instructor in advance. Permission of instructor required. Typically offered Fall Spring Summer.
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BIOL 49900 - Biology Honors Thesis Research
Credit Hours: 1.00 to 4.00. Research under the guidance of a scientist. Submission of honors tutorial petition and consent of faculty tutor and Honors Committee. Permission of department required. Typically offered Fall Spring Summer.
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BIOL 50000 - Modular Upper-Division Laboratory Course
Credit Hours: 2.00. This is a project-oriented course designed to give the student exposure to laboratory research through a series of five-week modules. The student must complete the introductory five-week module or have consent of instructor before taking the other modules. Typically offered Summer Fall Spring.
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BIOL 51100 - Introduction To X-Ray Crystallography
Credit Hours: 3.00. (EAPS 51100 ) Analysis of two- and three-dimensionally ordered structures by optical, electron, and X-ray diffraction methods. Geometry of diffraction. Detection of diffraction. Intensity of diffracted waves. Symmetry of crystals. The phase problem. The heavy atom method. Isomorphous replacement. Direct methods. Molecular replacement. Helical diffraction. Typically offered Fall.
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BIOL 51500 - Molecular Genetics
Credit Hours: 2.00 (West Lafayette) 3.00 (Fort Wayne) A molecular approach to the problems of structure, duplication, mutation, and phenotypic expression of generic material. Typically offered Spring.
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BIOL 51600 - Molecular Biology Of Cancer
Credit Hours: 3.00. A detailed course examining the molecular mechanisms controlling the growth of animal cells. Emphasis will be placed on current experimental approaches to defining the molecular basis of growth regulation in developing systems and the uncontrolled proliferation of cells in metabolic disorders, such as cancer. Typically offered Spring.
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BIOL 51700 - Molecular Biology: Proteins
Credit Hours: 2.00. Principles of protein three-dimensional architecture. The molecular and structural basis of protein folding, function, and evolution. Typically offered Spring.
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BIOL 52900 - Bacterial Physiology
Credit Hours: 3.00. A detailed consideration of the central metabolic routes, their role in generation of energy and key intermediates, and the conversion of those intermediates to small molecule building blocks. Regulatory mechanisms will be stressed. Typically offered Fall.
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BIOL 53100 - Parasitology
Credit Hours: 4.00. Arthropod, protozoan, and helminth parasites, their morphology, life histories, host-parasite relationships, and control. Typically offered Fall.
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BIOL 53300 - Medical Microbiology
Credit Hours: 3.00. Host-parasite relationships. Immunology. Bacteria and viruses associated with infectious diseases. Typically offered Fall.
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BIOL 53700 - Immunobiology
Credit Hours: 3.00. Readings and discussion in the structural, cellular, and genetic basis of the immune response. BIOL 42000 recommended as a pre-requisite. Typically offered Spring.
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BIOL 53800 - Molecular, Cellular, And Developmental Neurobiology
Credit Hours: 3.00. Molecular mechanisms of neural cell biology and development are considered. Topics and readings are drawn from the current primary literature. BIOL 42000 recommended as a pre-requisite. Typically offered Spring.
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BIOL 54100 - Molecular Genetics Of Bacteria
Credit Hours: 3.00. Advanced bacterial genetics, with emphasis on the use of genetics as a powerful and creative intellectual activity that enables us to discover biological functions and to construct new organisms by the manipulation of DNA. Major topics include: mutations, genetic selections, recombination, regulatory mechanisms, and genomic evolution. Typically offered Fall.
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BIOL 54200 - Modular Upper-Division Laboratory Course
Credit Hours: 1.00 or 2.00. This is a project-oriented course designed to give the student exposure to laboratory research through a series of 5-week modules. The student must complete the introductory 5-week module or have the consent of the instructor before taking the other modules. Topics may include animal cell culture, cloning and blot analysis, DNA fingerprinting, analysis of nucleic acid sequences, animal physiology, bacterial genetics, advanced neurophysiology, chromatin structure, eukaryotic gene expression, genomics, yeast molecular biology, and molecular virology, etc. Typically offered Fall Spring.
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BIOL 54601 - Topics In Infectious Diseases
Credit Hours: 1.00. The course will discuss the history and current progress in infectious diseases with a focus on the cell biology of infectious diseases. Scientific publications will be selected based on their impact in the field and how it facilitates student learning. Students will acquire up-to-date knowledge of infectious diseases and be given instructional direction on how to select, read and present scientific findings. Typically offered Spring.
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BIOL 54900 - Microbial Ecology
Credit Hours: 2.00. A study of microbial interactions with other organisms and the environment. Aquatic and terrestrial ecosystems as well as interactions between nonpathogenic microbes and plants and animals will be discussed. Offered in alternate years. Typically offered Spring.
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BIOL 55000 - Plant Molecular Biology
Credit Hours: 3.00. A comprehensive study of plant molecular biology and plant molecular genetics. Topics will include the structure and expression of plant nuclear, chloroplast, and mitochondrial genomes, and plant viruses. Typically offered Spring.
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BIOL 55001 - Eukaryotic Molecular Biology
Credit Hours: 3.00. This is a general survey course intended for advanced undergrads and beginning grad students. The course will draw upon examples from the plant, animal, and fungal kingdoms, and will familiarize students with the basic principles of molecular biology analyses as they apply to eukaryotic organisms. By the end of the course students should have knowledge of these molecular processes and should be able to design and analyze experiments dealing with these topics. This is not a first course in molecular biology. Typically offered Spring.
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BIOL 55900 - Endocrinology
Credit Hours: 3.00. The study of hormone function. Consideration will be given to the role of hormones in growth, development, metabolism, homeostasis, and reproduction. Typically offered Fall.
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BIOL 56200 - Neural Systems
Credit Hours: 3.00. (SLHS 50700, PSY 51200 ) Overview of the structure and function of neural systems including those involved with motor, somatosensory, visual, auditory, learning, memory, and higher cortical processes. Molecular and cellular aspects of neural function are integrated with discussion of relevant neuroanatomy. Background in cell biology, psychobiology, physiology or anatomy is recommended. Typically offered Spring.
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BIOL 56310 - Protein Bioinformatics
Credit Hours: 3.00. Accumulation of biological data, such as genome sequences, protein structures and sequences, metabolic pathways, opened up a new way of research in biology-bioinformatics. Through the survey of the various active research topics in bioinformatics, in this course we will learn bioinformatics databases, tools, and algorithms behind these tools. Special emphasis is placed on protein sequence and structure analyses. Covered topics will include methods for protein sequence comparison, protein structure comparison, protein structure prediction/modeling, protein docking prediction, protein function prediction, and protein network analysis. Typically offered Spring.
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BIOL 56600 - Developmental Biology
Credit Hours: 3.00 (West Lafayette, Fort Wayne, IUPUI, North Central)
4.00 (Calumet) Principles of development with emphasis on concepts and experimental evidence for underlying mechanisms, including molecular, cellular, and supracellular approaches. Typically offered Spring.
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BIOL 56700 - Laboratory In Developmental Biology
Credit Hours: 1.00. Descriptive and experimental study of the development of animals. Laboratories do not necessarily follow lecture material. Typically offered Spring.
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BIOL 57300 - The Molecular Biology Of Animal Cells
Credit Hours: 3.00. Structure and organization of the genome, chromatin structure, the expression and regulation of genes. Typically offered Fall.
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BIOL 58000 - Evolution
Credit Hours: 3.00. A study of evolution as a basic concept of the biological sciences; an examination of current methods of experimentation within the area, as well as evidences for the possible mechanisms of evolutionary change. Typically offered Spring.
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BIOL 58010 - Teaching Evolution: Online Course
Credit Hours: 3.00. Evolution is one of the most important and most widely misunderstood concepts in science. Teaching Evolution is an online course to help you deepen your understanding of evolutionary concepts, develop instructional strategies, and address obstacles in the teaching of evolution. Typically offered Fall Spring Summer.
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BIOL 58210 - Ecological Statistics
Credit Hours: 3.00. This course covers topics that are useful for successfully designing and analyzing statistically observational and experimental studies in ecology, animal behavior, evolutionary biology, forestry, wildlife sciences, fisheries, etc. Some topics are: differences between hypotheses and predictions, design of an ecological study, general linear models, assumptions, different types of designs (factorial, nested, repeated measures, blocks, split-plots, etc.). fitting models to data, etc. The course will focus on the conceptual understanding of these topics (e.g., interpreting the results of statistical tests) and practice with statistical programs and real datasets. Typically offered Fall.
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BIOL 58500 - Ecology
Credit Hours: 3.00. Ecological processes and dynamics of populations, communities, and ecosystems; physical, physiological, behavioral, and population genetic factors regulating population and community structure; case studies; field studies, and simulation models of life history attributes, competition, predation, parasitism, and mutualism. Typically offered Fall.
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BIOL 58705 - Animal Communication
Credit Hours: 3.00. This course will be a broad-scaled analysis of animal communication. Topics will include the physics of sound- and light-signal production, propagation and reception of signals, the use of communication as a means of information transfer, and the evolution of signaling systems. Mathematical principles are covered (e.g. in the evolution of signals), so some background in mathematics (e.g. calculus or algebra and introductory physics) is helpful. Typically offered Fall.
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BIOL 59100 - Field Ecology
Credit Hours: 4.00. A field course in ecology that stresses natural history and testing ecological theory under natural conditions. Group and individual projects include observational and experimental approaches. Emphasis is on the study of plant and animal species interactions in terrestrial (including montane and coastal) and aquatic habitats. Issues in community, population, behavioral, and conservation biology are addressed. Several all-day Saturday and two weekend field trips. Offered in alternate years. Permission of instructor required. Typically offered Fall.
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BIOL 59200 - The Evolution Of Behavior
Credit Hours: 3.00. An investigation of behaviors as adaptations: specializations of sensory and motor mechanisms involved in behavior; animal communication systems; behavioral ecology; patterns of social behavior as solutions to ecological problems, such as predator avoidance and resource exploitation. Emphasis will be on theoretical principles; examples will be broadly comparative, ranging from microorganisms to mammals. Offered in alternate years. Typically offered Spring.
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BIOL 59500 - Special Assignments
Arrange Hours and Credit. Special work, such as directed reading, independent study or research, supervised library, laboratory, or field work, or presentation of material not available in the formal courses of the department. The field in which work is offered will be indicated in the student’s record. Permission of instructor required. Typically offered Fall Spring Summer.
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BIOL 59700 - Sex And Evolution
Credit Hours: 3.00. Covers various theoretical and empirical aspects of sexual reproduction from an evolutionary perspective. Topics include: Why did sexual reproduction evolve? What different modes of reproduction exist? How is the sex of an individual determined in different organisms? What sex ratio should exist in different species? What is sexual selection, and how does it influence male and female characteristics in various species? How does sexual selection influence human social behavior?. Typically offered Fall.
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BIOL 59900 - Quantitative Physiology
Credit Hours: 3.00. This course is designed to give upper-division biological sciences and biomedical engineers the ability to quantitatively understand the physical and chemical factors that are responsible for living systems. Normal relationships, both empirical and theoretical, will be covered primarily. This foundation in normal physiological systems is complemented by subsequent topics on system pathologies. Typically offered Spring.
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BIOL 60000 - Bioenergetics
Credit Hours: 2.00. Energy transduction in biological membranes: physical chemical foundations; electron transfer, proton translocation; and active transport. Atomic structures of integral membrane protein complexes responsible for respiratory, photosynthetic generation of electrochemical potential; ATPase motor, and structure-based mechanisms. Offered in alternate years. Prerequisite: BCHM 56100 , BCHM 56200 and CHM 37300 . Typically offered Fall.
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BIOL 60200 - Cellular Neurobiology
Credit Hours: 3.00. This course covers principles of neurophysiology and cell, molecular and developmental neurobiology for graduate students from a wide range of disciplines. Course material will involve lectures and assigned textbook readings, homework problems and in-class discussions based on selected readings of the primary literature, and computer-based simulations of neurophysiology. Grades will be based on participation in class discussions, graded homework sets and exams (a midterm and a final exam). Typically offered Fall.
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BIOL 61100 - Crystallography Of Macromolecules
Credit Hours: 3.00. The special techniques required in the structure determination of biological macromolecules. Symmetry of macromolecules. Data collection and processing. The isomorphous replacement technique. The molecular replacement technique. Use of anomalous dispersion. Restraint and constraint refinement. Computational techniques. Prerequisite: BIOL 51100 . Permission of instructor required. Typically offered Fall.
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BIOL 62000 - Advanced Topics In Eukaryotic Cell Biology
Credit Hours: 3.00. A study of current areas of cell biological research, including the cytoskeleton, the regulation of the cell cycle, and the functions and dynamics of membrane-bound organelles. Typically offered Spring.
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BIOL 64700 - Membrane Protein Structural Biology
Credit Hours: 2.00. This course focuses on the structural basis of the functions and dysfunctions of diverse membrane proteins, analyzed by X-ray, electron microscopy, and spectroscopy. The functions include transport, biogenesis, and transmembrane signaling. Unique problems associated with the structure analysis of integral membrane proteins are discussed. Typically offered Spring.
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BIOL 65001 - Techniques In Molecular Biology
Credit Hours: 1.00. Techniques in Molecular Biology will introduce graduate students to the theory and practice of many commonly used methods. Emphasis will be placed on understanding the theoretical basis for these techniques, their utility in various circumstances, and their limitations. Although taught as a lecture, students should be able to take this knowledge back to the laboratory to help them in their research efforts. The course will be as close as possible to a laboratory experience without being in an actual laboratory setting. This course is designed to prepare students for other in-depth 600-level scientific courses, for their rotations, and for future laboratory work. Exams will be “experimental” in nature (e.g., “design and experiment to do something…” or “in this type of situation, which technique/vector/etc. would best be used, and why…”). Typically offered Fall.
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BIOL 65200 - Advanced Ecology Discussion
Credit Hours: 1.00. Weekly meetings to discuss and evaluate seminal papers in the fields of evolutionary, population, and community ecology. During the last week, students will critically evaluate a contemporary paper on a topic related to the “classic” papers discussed during the semester. Students will have a choice among papers submitted by participating faculty members; their critique will be assessed on content, originality, rigor, and clarity. Typically offered Fall.
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BIOL 65300 - Advanced Evolution Discussion
Credit Hours: 1.00. Weekly meetings to discuss and evaluate seminal papers in the fields of evolution and population biology. During the last week, students will critically evaluate a contemporary paper on a topic related to the “classic” papers discussed during the semester. Students will have a choice among papers submitted by participating faculty members; their critique will be assessed on content, originality, rigor, and clarity. Typically offered Spring.
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BIOL 66200 - Seminar Methods And Professional Development I
Credit Hours: 1.00. An introduction for incoming graduate students to methods of seminar presentation and critique and to various guidelines for professional development during their graduate school experience. Topics include research laboratory safety (REM), how to give a talk, acclimating to graduate studies (especially time management), how to select a major professor and an advisory committee, how to prepare for qualifying exams, Purdue University guidelines for responsible conduct of research, how to organize a poster presentation, how to negotiate with mentors, and expectations for success. The course also serves to socialize the incoming cohort of students among themselves and with more senior students in the broad range of research disciplines available. Typically offered Fall.
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BIOL 66300 - Seminar Methods And Professional Development II
Credit Hours: 1.00. This course is a continuation of BIOL 66200 and expands the introduction for incoming graduate students to methods of seminar presentation and critique and to various guidelines for professional development during their graduate school experience. Topics include seminar topic selection and 20-minute seminar design, tutorials on electronic services at the PU Library and Citation Management programs, and evaluating classmate presentations. Using the skills learned the previous semester, each student is required to make a 20-minute PowerPoint presentation to the class, based on a pre-approved topic of their choice. The speaker is asked questions and the presentation receives written evaluations by all members of the class. Each student practices with the course instructor prior to the public presentation. The course also continues to socialize the incoming cohort of students among themselves and with more senior students in the broad range of research disciplines available. Typically offered Spring.
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BIOL 68100 - Advanced Eukaryotic Genetics
Credit Hours: 3.00. This course is designed for graduate students who wish to refresh their knowledge of the fundamental principles of eukaryotic transmission and molecular genetics, to explore new and developing areas of genetic research in depth, and to learn of genetic tools that can be applied within their own research. Lecture materials will be supplemented with class discussions of primary literature. Topic areas comprise epigenetic phenomena, developmental genetics, and systems biology. Typically offered Spring.
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BIOL 69100 - Biological Research Methods
Credit Hours: 1.00. Open to graduate students in the Department of Biological Sciences and designed primarily for students in their first year of graduate study. The course consists of two laboratory assignments, each of which lasts about two months. Students may take one or two of these per semester. During each laboratory assignment, the student will be exposed to methods, equipment, and experimental procedures currently in use in a particular departmental research laboratory selected by the student and through arrangement with the professor in charge of that laboratory. Admission by consent of the departmental Graduate and Advanced Studies Committee. Typically offered Fall Spring Summer.
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BIOL 69500 - Special Assignments
Arrange Hours and Credit. Special work, such as directed reading; independent study or research; supervised library, laboratory, or field work; or presentation of material not available in the formal courses of the department. The field in which work is offered will be indicated in the student’s record. Primarily for Ph.D. candidates. Permission of instructor required. Typically offered Fall Spring Summer.
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BIOL 69600 - Seminar
Credit Hours: 1.00. Each semester there are several separate seminar offerings. They will likely be on the following topics: biochemistry, crystallography, ecology and population biology, genetics, mechanisms of development, microbiology, neurobiology, and plant physiology. The student’s record will indicate the specific seminars in which he/she has participated. Oral presentations required. At least two credits are required of Ph.D. candidates. Typically offered Fall Spring.
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BIOL 69800 - Research MS Thesis
Credit Hours: 1.00 to 18.00. Research MS Thesis. Permission of instructor required. Typically offered Fall Spring Summer.
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BIOL 69900 - Research PhD Thesis
Credit Hours: 1.00 to 18.00. Research PhD Thesis. Permission of instructor required. Typically offered Fall Spring Summer.
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Biomedical Engineering |
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BME 19500 - Selected Topics In Biomedical Engineering
Credit Hours: 0.00 to 4.00. Specialized topic areas in BME for which there are not specific courses, workshops, or individual study plans, but having sufficient student interest to justify the formalized teaching of a course. Typically offered Fall Spring Summer.
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BME 20100 - Biomolecules: Structure, Function, And Engineering Applications
Credit Hours: 3.00. Classes of molecules (biomolecules) such as sugars, lipids, proteins, and nucleic acids that form the cellular components of living organisms. Explores the chemistry behind the structure and function of these important classes of biological molecules. Hydrogen-bonding, hydrophobic forces, electrostatis interactions along with other weak interactions discussed with reference to their importance in biomolecular systems in an engineering context. Typically offered Fall.
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BME 20400 - Biomechanics Of Hard And Soft Tissues
Credit Hours: 3.00. Covers the mechanics of biological materials, with applications in the musculo-skeletal system, nerves, spinal cord, and vascular tissue, down to the level of the cell. Topics include center of mass, moment of inertia, basic understanding of stresses, strains, and deformations, axial elements, pressure vessels, beams, torsion, viscoelasticity, and thermal stress. Case studies and problem solving sessions used to emphasize the unique biological criteria which must be considered when mechanically analyzing both soft and hard tissues. Typically offered Spring.
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BME 20500 - Biomolecular And Cellular Systems Laboratory
Credit Hours: 1.00. Introductory laboratory experience focused on engineering concepts and practices in the analysis of biomolecules and cells. Topics include fundamental quantitative techniques of analysis, methods of isolation, identification, and quantification of biomolecules and cells, and analysis of integrated biosystems. Concludes with student-driven design project. Typically offered Fall.
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BME 20600 - Biomechanics And Biomaterials Laboratory
Credit Hours: 1.00. Provides hands-on training in engineering and biological principles of biomaterials and biomechanics. Topics include evaluation and interpretation of experimental results, modeling and testing of tissue and body mechanics, and interactions of living (e.g., tissue/cell) and nonliving (e.g., biomaterial) systems. Typically offered Spring.
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BME 25600 - Physiological Modeling In Human Health
Credit Hours: 3.00. Introduction to the physiology and medicine underlying practical problems in biomedical engineering, especially with respect to medical device development. Engineering skills taught and practiced within the context of human disease, injury, and illness on extended problem sets which include mathematical modeling and problem solving with appropriate documentation. Main physiological systems of focus are cardiovascular, pulmonary, and renal, and common afflictions thereof. Typically offered Spring.
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BME 29000 - Frontiers In Biomedical Engineering
Credit Hours: 1.00. This course introduces the rapidly emerging field of biomedical engineering by exposing students to a wide range of research activities in the Weldon School and to a variety of experimental learning opportunities. Topics addressed include career paths, professional development opportunities, and career development skills including creating a plan of study, informational and job interviewing, writing a resume, technical writing, preparing effective oral presentations, and peer-editing. Typically offered Fall.
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BME 29500 - Selected Topics In Biomedical Engineering
Credit Hours: 1.00 to 4.00. Specialized topic areas for which there are no specific courses, workshops, or individual study plans, but having sufficient interest to justify the formalized teaching of a course. Permission of instructor required. Typically offered Summer Fall Spring.
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BME 29600 - Biomedical Engineering Projects
Credit Hours: 1.00 to 4.00. Individual research projects to be approved by the supervising faculty member before registering for the course. An approved written report is required. Permission of instructor required. Typically offered Summer Fall Spring.
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BME 30100 - Bioelectricity
Credit Hours: 3.00. Fundamentals of bioelectricity of the mammalian nervous system and other excitable tissues. Passive and active forms of electric signals in both the single cell and cell-cell communication, tissue and systematic bioelectricity, mathematical analysis including Nernst equation, Goldman equation, linear cable theory, and Hodgkin-Huxley Model of action potential generation and propagation. Typically offered Fall.
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BME 30400 - Biomedical Transport Fundamentals
Credit Hours: 3.00. Fundamental concepts and principles of momentum, heat, and mass transport phenomena in the context of biomedical applications. Integrated biological topics include transport of physiological fluids (e.g. blood), mass transport (e.g. oxygen and nutrients), forced convection (e.g. hemodialysis) and unsteady-state molecular diffusion (e.g. drug delivery mechanisms). Typically offered Fall.
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BME 30500 - Bioinstrumentation Circuit And Measurement Principles
Credit Hours: 3.00. Introduction of laboratory instruments used to measure physiological events. Stimulation and conduction of electric signals within the nervous system and other excitable tissues are demonstrated. Fundamental circuit elements and concepts include resistance, capacitance, inductance, op-amps, impedance, voltage, current, power, and frequency. Fundamental analog measurement concepts include adequate bandwidth and amplitude and phase linearity. An integrative two-week design project addresses the practical aspects of quantitative physiological measurements. Typically offered Fall.
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BME 30600 - Biotransport Laboratory
Credit Hours: 2.00. Practical experience with transport principles related to physiological systems is presented through inquiry-based modules. Modules contain elements of computer simulation, experimental design, implementation, and data analysis and address biomedical applications. Typically offered Spring.
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BME 38199 - Professional Practice Co-Op I
Credit Hours: 0.00. To obtain professional practice with qualified employers within industry, government, or small business. Professional Practice students only. Permission of instructor required. Typically offered Fall Spring Summer.
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BME 38299 - Professional Practice Co-Op II
Credit Hours: 0.00. To obtain professional practice with qualified employers within industry, government, or small business. Professional Practice students only. Permission of instructor required. Typically offered Fall Spring Summer.
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BME 38399 - Professional Practice Co-Op III
Credit Hours: 0.00. To obtain professional practice with qualified employers within industry, government, or small business. Professional Practice students only. Permission of instructor required. Typically offered Fall Spring Summer.
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BME 39000 - Professional Development And Design In Biomedical Engineering
Credit Hours: 1.00. Introduction to a diverse spectrum of current topics relevant to the technical, professional, and career aspects of Biomedical Engineers. The course topics will focus on the early stages of the design process (e.g. need identification, problem formulation, innovation and idea generation), professional communication skills (e.g. written and oral reporting and documentation), and ethics of biomedical design and research (e.g. ethical codes and decision making, animal care and use in research and testing, authorship and intellectual property, social and environmental impact of design). Typically offered Spring.
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BME 39500 - Selected Topics In Biomedical Engineering
Credit Hours: 1.00 to 4.00. Specialized topic areas for which there are no specific courses, workshops, or individual study plans, but having sufficient student interest to justify the formalized teaching of a course. Permission of instructor required. Typically offered Summer Fall Spring.
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BME 39699 - Professional Practice Internship
Credit Hours: 0.00. To obtain professional practice with qualified employers within industry, government, or small business. Permission of department required. Typically offered Fall Spring Summer.
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BME 40100 - Mathematical & Computational Analysis Of Complex System Dynamics In Biology, Medicine, & Healthcare
Credit Hours: 3.00. An introduction to analysis of complex system dynamics that appear in biology, medicine, and healthcare. Key topics include nonlinear dynamical concepts associated with phase plane, bifurcation, stability diagram, oscillation, and chaotic systems along with concepts from discrete systems and stochastic processes. These topics are taught within the context of mathematical and computational models related to both non-communicable diseases (i.e. cancer) and communicable diseases (i.e. HIV/AIDS). Courses projects are drawn from recent literature. Typically offered Fall Spring.
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BME 40500 - Biomedical Engineering Design Project
Credit Hours: 4.00. Design and management of biomedical engineering projects. Teams design and implement a solution to a biomedical engineering problem utilizing skills gained in previous course work. Oral and written presentation of design and demonstration of function are required. Typically offered Fall Spring.
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BME 48800 - Preliminary Senior Project Design
Credit Hours: 1.00. The preliminary stages of design are completed during these lab hours. Students will work with their teammates to develop a problem statement with appropriate technical specifications, complete the relevant literature and market analysis, derive and justify a preliminary design, and outline a plan to successfully complete the project. The resulting preliminary design is presented and evaluated through an oral presentation and a written report. Typically offered Fall.
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BME 48900 - Senior Design Project Lab
Credit Hours: 2.00. The biomedical engineering design process is completed starting from a preliminary system design. Student will work with their teammates to implement (e.g. build, test, iterate and evaluate) a solution to address a biomedical engineering problem statement and meet the technical specifications set forth. The resulting project design is presented and evaluated through an oral presentation, laboratory demonstration, and a final written document. Typically offered Fall Spring.
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BME 49000 - Professional Elements Of Design
Credit Hours: 1.00. This course advances and enhances design tools, concepts, and knowledge relevant to biomedical engineering design. Students work individually and in small teams to investigate the topic within the context of their specific senior design project in preparation for their lab. Topics include project management, human and animal subjects, ethics, regulatory affairs, literature and patent searching, and entrepreneurship. Typically offered Fall.
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BME 49500 - Selected Topics In Biomedical Engineering
Credit Hours: 1.00 to 4.00. Specialized topic areas for which there are no specific courses, workshops, or individual study plans, but having sufficient student interest to justify the formalized teaching of a course. Permission of instructor required. Typically offered Summer Fall Spring.
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BME 49800 - Biomedical Engineering Projects
Credit Hours: 1.00 to 4.00. Individual research projects to be approved by the supervising faculty member before registering for the course. An approved written report is required.
. Permission of instructor required. Typically offered Summer Fall Spring.
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BME 52100 - Biosensors: Fundamentals And Applications
Credit Hours: 3.00. (ABE 56000 ) An introduction to the field of biosensors and an in-depth and quantitative view of device design and performance analysis. An overview of the current state of the art to enable continuation into advanced biosensor work and design. Topics emphasize biomedical, bioprocessing, environmental, food safety, and biosecurity applications. Typically offered Spring.
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BME 52800 - Measurement And Stimulation Of The Nervous System
Credit Hours: 3.00. (ECE 52800 ) Engineering principles addressing questions of clinical significance in the nervous system: neuroanatomy, fundamental properties of excitable tissues, hearing, vision, motor function, electrical and magnetic stimulation, functional neuroimaging, disorders of the nervous system, development and refinement of sensory prostheses. Typically offered Spring.
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BME 54000 - Biomechanics
Credit Hours: 3.00. Application of engineering mechanics to the study of normal and diseased musculoskeletal systems, including bone and soft tissue biology, musculoskeletal statics and dynamics, mechanical properties of biological tissues, and structural analysis of bone-implant systems. Permission of instructor required. Typically offered Fall.
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